Choosing the Right Stool Test in Clinical Practice: Understanding Diagnostic vs Microbiome Sequencing Technologies

Not all stool tests are designed for the same clinical purpose.

As microbiome sequencing has become more widely available, many practitioners are left navigating reports rich in data — but often limited in diagnostic clarity.

In this masterclass, Dr. Dan Kalish examines the fundamental differences between microbiome sequencing tests and quantitative, diagnostic stool testing, with a focus on how test methodology impacts real-world clinical decision-making.

Using GI-MAP® as an example of a qPCR-based diagnostic stool test, Dr. Kalish will explore:

1. How stool testing technologies differ — and why methodology matters
2. The limitations of relative abundance data in clinical diagnostics
3. What makes a stool test clinically actionable versus informational
4. How qPCR evaluates pathogen load, virulence factors, and clinical relevance
5. When microbiome sequencing may be helpful — and when a diagnostic test is required

Designed for functional and integrative practitioners, this masterclass provides a clear framework for evaluating stool tests so you can choose the right tool for the right clinical application — with greater confidence and clarity.